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Advanced Skin Medspa
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Laser

PicoGenesis

A picosecond laser for sun spots, discoloration and dark patches.

  • The full guide
  • Questions, answered
  • Complimentary consultation in Fishkill
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PicoGenesis

At a glance

Sessions
Two to three sessions, four to six weeks apart
Time in the chair
20 to 30 minutes
Prices from
$350

The short version

PicoGenesis uses very short pulses of light. People ask about it for sun spots, discoloration and dark patches.

Most people want to know

All the questions

How PicoGenesis works

PicoGenesis uses picosecond laser technology to deliver ultra-short bursts of energy measured in trillionths of a second.

This is significantly faster than traditional nanosecond lasers, which deliver pulses measured in billionths of a second. The difference in pulse duration has a profound effect on how pigment is disrupted. While nanosecond lasers primarily break down pigment through photothermal (heat-based) mechanisms, picosecond pulses generate a photomechanical (pressure-based) effect that shatters melanin particles into much finer fragments. These microscopic particles are then more efficiently recognized and cleared by the body’s natural immune system.

The Cutera enlighten platform used for PicoGenesis treatments delivers dual wavelengths (532nm and 1064nm) to target pigment at different depths within the skin. The 532nm wavelength is highly effective for superficial pigmentation such as sun spots, freckles, and epidermal melasma, while the 1064nm wavelength reaches deeper pigment deposits in the dermis. By combining these wavelengths in a single treatment session, PicoGenesis addresses the full spectrum of pigmentation concerns while also stimulating collagen production for an overall improvement in skin tone, texture, and luminosity.

PicoGenesis

Conditions treated with PicoGenesis

PicoGenesis is specifically designed to address pigmentation-related skin concerns.

Sun spots and age spots, the flat brown patches that develop on areas of chronic sun exposure such as the face, hands, chest, and forearms, respond very well to picosecond energy. Freckles, whether genetic or sun-induced, can be significantly lightened or cleared. Uneven skin tone and diffuse hyperpigmentation, where the overall complexion appears blotchy or discolored, are dramatically improved as the laser breaks down irregularly distributed melanin throughout the treated area.

Melasma, one of the most challenging pigmentation conditions to treat, can be addressed with PicoGenesis when used at appropriate settings. The photomechanical mechanism of picosecond lasers generates less heat than traditional lasers, which is advantageous for melasma because excessive heat can actually trigger melasma to worsen. For patients throughout the Hudson Valley who have spent years accumulating sun damage and pigmentation changes, PicoGenesis offers a powerful corrective solution that restores the clear, even complexion of younger skin. Beyond pigmentation correction, patients consistently report an overall improvement in skin radiance, smoothness, and quality following a PicoGenesis series.

Your PicoGenesis treatment experience

PicoGenesis treatments are relatively quick and well-tolerated.

A topical numbing cream may be applied before the procedure depending on the treatment area and patient sensitivity, though many patients find the treatment comfortable without numbing. The laser handpiece is passed over the treatment area, delivering rapid pulses of picosecond energy. Patients typically describe the sensation as a series of quick snapping or tingling sensations. A full facial treatment takes approximately 20 to 30 minutes, with shorter times for targeted spot treatments on smaller areas.

Immediately after treatment, the treated pigmented areas typically darken and may appear slightly raised. The surrounding skin may show mild redness that resolves within a few hours. Over the following five to seven days, the darkened pigmented spots gradually flake off and shed, revealing clearer, more evenly toned skin beneath. There is minimal downtime, and most patients return to normal activities immediately, though mineral sunscreen must be applied diligently. A series of two to three treatments spaced four to six weeks apart is typically recommended for optimal pigmentation clearance, though some patients notice significant improvement after a single session.

PicoGenesis
PicoGenesis

Why people choose PicoGenesis here.

Everyone who treats you here is licensed. The practice was founded by a clinical laser trainer who teaches other practices, and training is how this team works.

  • Ultra-short pulse precision

    Picosecond pulses shatter melanin into finer particles than traditional lasers, enabling more efficient clearance by the body’s natural processes and often requiring fewer treatment sessions.

  • Dual wavelength versatility

    The Cutera enlighten platform delivers both 532nm and 1064nm wavelengths to target pigment at multiple depths, addressing everything from superficial sun spots to deeper dermal pigmentation.

  • Minimal downtime

    Most patients return to normal activities immediately after treatment. Treated spots darken and flake off over five to seven days, but the process does not prevent daily activities or require social isolation.

  • Reduced heat, lower risk

    The photomechanical mechanism of picosecond energy generates less tissue heat than traditional lasers, reducing the risk of post-inflammatory hyperpigmentation and expanding the range of treatable skin types.

  • Bonus collagen stimulation

    Beyond pigment clearance, the photomechanical effect stimulates new collagen and elastin production, improving overall skin texture, firmness, and radiance as a secondary benefit.

  • Fast, efficient treatments

    A full facial PicoGenesis treatment takes just 20 to 30 minutes, making it a convenient option that fits easily into a busy schedule without sacrificing effectiveness.

Meet the team

Pricing guide

PicoGenesis, at Advanced Skin Medspa. List prices, checked September 2026.

  • PicoGenesis skin revitalization$350
  • Pico and Laser Genesis combination$500

Menu prices are starting points from our booking page and can change. Your plan, and the real number, come from your consultation. Credit cards carry a 3.5 percent non-cash fee.

Book a complimentary consultation

Not sure PicoGenesis is the one? That is what the consultation is for. Sometimes the honest answer is something else, or nothing yet.

Who treats you. A licensed team that learns the lasers from our founder, who trains other practices on this technology for Cutera and for Learn Aesthetics. Meet the team

Questions about PicoGenesis?

Dalia is our smart assistant. It can explain what this is and how booking works. Whether it is right for you is a conversation for your provider.

What people ask about PicoGenesis.

General answers, for learning. What fits you is decided in person, at a complimentary consultation.

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How many PicoGenesis treatments will I need?

Most patients achieve optimal results with two to three PicoGenesis treatments spaced four to six weeks apart. Some patients with lighter pigmentation may see significant improvement after a single session, while others with more extensive or deeper pigmentation may benefit from additional treatments. During your consultation, your provider will evaluate your pigmentation and recommend the appropriate number of sessions. Call (845) 392-2111 to schedule.

Is PicoGenesis safe for darker skin tones?

The picosecond mechanism generates less heat than traditional nanosecond lasers, which expands the range of skin types that can be safely treated. However, darker skin tones do carry a higher risk of post-inflammatory hyperpigmentation with any laser treatment. Your provider here will perform a thorough skin assessment and may recommend a test spot or modified treatment parameters for patients with deeper skin tones to ensure the safest, most effective approach.

What should I expect after a PicoGenesis treatment?

Immediately after treatment, targeted pigmented spots will darken and may appear slightly raised. Mild redness in the surrounding skin typically resolves within a few hours. Over the next five to seven days, the darkened spots gradually crust and flake off, revealing clearer skin beneath. It is essential to apply broad-spectrum sunscreen diligently and avoid direct sun exposure during the healing period to protect the treated skin and prevent new pigmentation from developing.

Can PicoGenesis treat melasma?

PicoGenesis can be used as part of a full melasma management plan. The lower heat profile of picosecond energy makes it a more suitable laser option for melasma compared to traditional lasers that generate more thermal energy. However, melasma is a chronic condition that requires ongoing management including sun protection, appropriate skincare, and sometimes topical prescription products. Your provider will discuss whether PicoGenesis is appropriate for your specific type of melasma and what complementary measures will optimize your results.

Will the pigmentation come back after PicoGenesis?

PicoGenesis effectively clears existing pigmentation, but it does not prevent new pigmentation from forming. Continued sun exposure without adequate protection will cause new sun spots and discoloration to develop over time. To maintain your results, daily broad-spectrum sunscreen is essential, along with sun-protective habits such as wearing hats and avoiding peak sun hours. Many patients schedule periodic maintenance treatments once or twice a year to address any new pigmentation before it accumulates.

Can PicoGenesis be combined with other treatments?

Yes. PicoGenesis pairs well with a variety of other treatments for full skin rejuvenation. It is frequently combined with Laser Genesis for simultaneous pigmentation correction and collagen stimulation, and it complements medical-grade skincare regimens that include brightening and pigment-inhibiting ingredients. Your provider here will recommend the most effective combination approach based on your individual concerns and goals.

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Ask Dalia anything.

Every treatment, what it costs, how long it takes, how booking works. Ask at any hour. When it is a question for a person, Dalia gets you one.

Dalia is our smart assistant. It answers from what the practice has published, and gets a person when you need one.